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Microdosing GLP-1s Like Wegovy, Zepbound May Still Lead to Weight Loss. Research shows that microdosing GLP-1 medications may still lead to weight loss. Tatsiana Volkava · Moment/Getty Recent research suggests that people may still lose weight while staying on the lowest starting doses of GLP-1 medications, such as Wegovy or Zepbound, for longer periods. After one year, people taking sustained low dose tirzepatide lost about 5.5% of their body weight, while those taking sustained low dose semaglutide lost about 2.2%. Lower doses were associated with more modest weight loss than higher doses, but sustained low dose semaglutide was also associated.

8-Hour Time-Restricted Eating Window May Lead to Greater Weight Loss. Research shows that an 8-hour eating window may lead to greater weight loss than other time-restricted eating patterns. FreshSplash · E+/Getty An 8-hour eating window was linked to greater weight loss than a 12-hour window or no time restriction, but not significantly more than a 10-hour window. Time-restricted eating (TRE) is a form of intermittent fasting that limits eating to a set number of hours each day without necessarily restricting calories. Shorter eating windows were linked to modest weight loss, but researchers found limited effects on blood pressure, blood sugar,.

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